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Can Arterial Disease Be Reversed?

Can Arterial Disease be Reversed?

If your body can mend a bone, heal a cut, regrow muscle, and even recover from brain injury, why can’t it naturally reverse cardiovascular disease?

It can. But you haven’t heard this. Why not? Because there are two competing models of atherosclerosis. The old model describes arteries as so many mechanical tubes that have no way to protect themselves from the inevitable clogging that comes from the consumption of cholesterol and saturated fat. The other, new model recognizes the role of blood sugar in damaging arteries large and small, and explains why diabetics are in the highest risk category for heart attacks and strokes even if their cholesterol levels are normal. What’s more interesting, perhaps because it is more hopeful, is the fact that the new model acknowledges arteries as living dynamic tissue that, in the context of a healthy diet, is capable of growth, repair, and rising to the challenge of rigorous exercise.

Atherosclerosis is not a “buildup” of fat in your arteries.

You might have heard that fatty foods cause arterial fat deposits just like kitchen grease you rinse down the drain, which, over time, builds up to clog the pipe. When you have a clogged pipe you simply bust through the clog with a plumbing snake or Draino. It would make sense to treat your body this way were your arteries anything like the plumbing under your sink.

But your arteries are nothing like the plumbing under your sink, and using the term “blocked arteries” can be very misleading. Why is that? Because once you’ve got this misleading image of clogged plumbing in your mind, the router-router treatment (surgery, whether angioplasty or stenting) can seem like a valuable intervention to a prevent heart attacks or strokes. In reality, atherosclerosis is not simply a buildup of debris that can be scooped out. Atherosclerosis is the result of scar tissue formation within the wall of an artery. And so attempting to remove plaque, by way of surgical intervention risks damaging the weakened underlying tissue.

Before a patient undergoes angioplasty or stent placement, he is warned of potential complications of the procedure. Those complications include heart attack, stroke, and death. When will those complications occur? When the surgeon manipulates a damaged artery so that the integrity of the repair is compromised. In extreme cases, the risk of surgery is less than the risk of death from atherosclerosis. But in my opinion those cases are few and far between because most people with atherosclerosis can get better results without resorting to interventions that create permanent anatomical changes to the structure of your arteries.

Even Blockages Like This Can Be Stablized and Reversed With an Anti-Inflammatory Diet

Your Body Can Heal Arterial Damage No Matter Your Age

Your body can recover from arterial damage by making two distinct types of accommodations.

First, it may bypass the damaged and narrowed artery by expanding existing collateral arteries supplying the same tissue, kind of like widening a highway to accommodate increased traffic into the city center. We see evidence of this occurring all the time when we do angiograms. Smoking or unhealthy eating makes it harder for your body to do this.

The second process is one in which the body actually heals the damaged section of artery. You’ve seen something very similar if you’ve ever gotten a deep cut in your skin down to the fat. First, a messy scab forms and, over time, typically 6 months or so, the skin around the injury grows inward to close the gap. Smoking and bad diet disrupt these processes as well.

Atherosclerotic plaque forms not from cholesterol build up but from arterial damage.

Sometimes I wish there were scientific validity to the cholesterol building up inside the pipe model; it’s so much easier to explain to people. In reality, however, the body is more complicated.

Plaques form inside arteries in locations where the artery was, at some point in the past, acutely damaged by deposits of highly irritating pro-inflammatory fats that splatter on the insides of your arteries. These splattered fats annoy the arterial lining cells that they’ve landed on. To remove these caustic chemicals, the defiled cells release a cascade of inflammatory signals that communicate their need for help. Specialized cells then arrive to remove the offending fats and get the inflammation in your arteries under control.

Time is of the essence here and the process is very delicately balanced because, if repairs are not made before a micro-hemorrhage tears the collagen supporting your artery, a deadly blood clot may form. (Pages 192-198 of Deep Nutrition gives a play-by-play pictorial of this process.)

It Matters If Your Plaques Are Stable or Unstable

You’ve probably heard of stable and unstable plaque in the context of discussions of atherosclerosis.

When the body is allowed to repair damaged arterial walls uninterrupted, it can produce a stable plaque, constructed of a robust coat of protein surrounding an ever-shrinking fatty core. This serves as a long-term fix until such time that the body can replace the patch with healthy arterial tissue.

In the context of a bad diet and/or smoking, this process is continually disrupted forcing the body to make due with suboptimal solutions. And so it cobbles together a tenuously thin protein coat surrounding the fatty core of the plaque. Much like an emergency repair made to a breached hull of a ship in high seas, this coating is a temporary fix only, and unlikely to last very long.

Stable plaques are not a threat to your health. But here’s the problem: Using the the tools currently available for diagnosing atherosclerosis in clinical practice, angiograms and carotid ultrasounds, there’s no way to tell if a plaque is stable or unstable. Therefore, since the cardiologists who I trust don’t recommend stenting a stable plaque, I’m not enamored with the idea of stenting on the basis of an angiogram alone.

The modern American diet is wrecking your heart.

The combination of excessive carb and vegetable oil intake creates the perfect chemical assault on your arteries. The time to take heart health seriously is now, before you are feeling any symptoms. To find how exactly how, read chapters Eight and Nine in Deep Nutrition. (Now available at a discount price on Our book also helps put today’s most popular diet, the Paleo Diet, in context of other traditional diets so that you can recognize where to tweak the Paleo diet to get the most health benefit.

Five things you need to know about atherosclerosis:

  • Your body can reverse even advanced disease naturally
  • You are never to old to strengthen your heart and circulatory system
  • Smoking is bad. But in the context of a bad diet smoking is 100x worse
  • The time to think about cardiovascular health is before you feel any symptoms
  • Your arteries are living dynamic tissue that can respond favorably to the right signals

Read Chapters 7 and 9 of Deep Nutrition to learn how traditional foods will help you Reverse Atherosclerosis, Naturally!

Dr. Cate

With over two decades of clinical experience and expertise in genetic and biochemical research, Dr. Cate can help you to reverse metabolic disease and reshape your body.

This Post Has 33 Comments

  1. […] Can Arterial Disease Be Reversed? | – New insights into the role of diet and heart disease highlight inflammation, not cholesterol, as the cause of heart disease, atherosclerosis, and heart attacks. […]

  2. Dr. Cate,
    Nice article on heart health and the reversal of arterial disease. I am currently having a tough time finding answers to many question in this area. I am recently having heart issue symptoms and will be seeing a cardiologist in a week – earliest I could get an appointment! Anyway, I have never smoked and at least since college I have had a really good diet and exercise regime but have a bad family history. By the way, I am turning 61 in a month. This all started with Afib and now a delay in EKG. So I am on a quest to find answers before jumping into an ablative procedure and a pacemaker. I had a Cardiac CT scan 3years ago just because I wanted to know where I was due to family history. Well it was pretty good showing only one 25% blockage in one artery. I have had two thalium stress tests over the years – no issues noted. So in my mind something is causing all this and just fixing it by treating the symptoms with a pacemaker and ablation is not a long term answer. My question is, how do I get the answers I am looking for? Not having a lot of luck so far with the medical profession. It takes time and effort to sort out things like this but time or lack of it seems to be a big road block. The effort seems only possible if my insurance decides to let a doctor run the tests that might be necessary. Without that and the time, so far, everyone just wants to do procedures that may or may not stop the symptoms and even if they worked it still is not addressing the actual cause of the problem. Where can I go to find help in identifying the cause of the problem?
    John B.

  3. Hello Dr Cate,

    This is the first time I have come across your article, and though while my issue is not regarding directly to my heart but to my right leg. For some time now my leg had been swelling and I was unsure why, after going to the Doctors for some time they noticed a blockage between my bladder and kidney (caused one kidney to fail, don’t know what the blockage was, opened with a stent) and my leg had a blocked arterie. Apparently veins have been formed around it. I haven’t gone in for any other tests as im fearful and scared. At that time I did smoke and had a bad diet, but now I don’t smoke (for a few years) and my diet is really good (trying to follow raw food diet, but still have bad food sometimes) My swelling isn’t as bad, but sometimes if I stand for too long its still swells. My question is, can it be fixed? It’s been 3 years or so, and im really not sure if any difference has been made, and if not, then should I really follow a strict diet?

    1. Good news: This is a diet-induced problem and it can be reversed by following a better diet. The more you improve and the more you stay disciplined (and this includes safe exercise), the faster you will get better.

  4. Thank you so much for your answer. I feel better now.
    I will get the Deep Nutrition book so I can learn Thanks again more about nutrition.

  5. I just had the results on my carotid artery test and the summary was the following. NON OBSTRUCTIVE LEFT NULB PLAQUES:INTIMAL THICKENING.
    I was told to keep on exercising and taking the statin(crestor).
    Is this diagnosis critical or what. I need more explanation on this matter please.

    1. The short answer is it’s probably not critical or your doctors would have told you to get surgery. It sounds like you could benefit from learning more about the process of atherosclerosis itself. There are a lot of misconceptions and even within the medical literature important details are left out. We wrote about this in detail in Chapter 8 of Deep Nutrition, and have been told the image on pages 196-7 is worth the price of the book.

  6. Hi. I am interested to know the 5 essential survival tools. My husband had a heart attack yesterday but thank God he got to the hospital before it worsened. I need all the resources I can get to know all about heart problems as I am away from my husband.

    Thanks a lot.

  7. Hi, in October i suffered from “mild keytosis” and at that time they found my tropone levels elevated. .14 and the following morning .29 they gave me both plavix and lopressor thus I didn’t have any say in the matter at the time ( I was unconscious when I arrived in the er) following morning I refused both of those drugs ( potential side effects make them too risky).

    I have been taking Hawthorn capsules ( 600 – 800mg daily I make my own capsules) q10, fish oil capsules and have reduced consumption of all forms of meat. but I also suffer from chest pains almost on a daily basis ( an angiogram showed I have 70 – 90% blockages in 4 of my arteries stents were ruled out in my case.). what other herbs and or supplements can I take to naturally revers the blockages…. my BP has gone from 130/70 to an average of 160/90 with highs of 225/111 i am either intolerant or allergic to statens, ace inhibitors, channel blockers and beta blockers. have been told by cardiologists that “they can’t do anything for me.”

    Running scared in Ontario Canada

  8. Hi my total cholesterol is 3.53 , HDL 1.28, Ldl 1.7, Triglycerides 1.17 Yet i had a heart attack.
    I am 5 ft 6.5 inch 154 lb. I did smoke at the time. I am male and 66 years old.

  9. Hi very interesting article and comments from others. I came across this article while searching for answers. I recently had a mild heart attack although to me it’s been anything but mild…I was in the ER clutching my chest. Well not really as my symptoms were more a tightness and dizzy spells anyway after settling my body down with some meds an angiogram was done and the found 30% blockage of the LAD and a 90% blockage in one of the branches after the first septal. I was of course awake for this and spoke with both the doctor performing the procedure and my attending cardiologist and both seemed rather non concerned about the 90% and both unanimously agreed to just leave it..this has me completely baffled why not fix it and what’s my future look like? So I guess what I’m asking Dr Cate is for those five essentials and perhaps you can shed some possible light as to why they would leave the blockage and what my future may hold…I should mention I’m a non smoker not over weight and had always exercised. I have however come to learn that my markers were there and just ignored or missed by my GP….oh well what’s done is done time to focus on the future..

  10. I had weird chest pains coming and going around my chest, center of chest, side of chest, sometimes down to my fingers, so my girl friend, an RN, insisted I go to the Wadsworth VA Hospital and get checked out. The ECG tests at the hospital were negative as well as consecutive blood tests, and while I was at the hospital overnight, my blood pressure went from 141 over 93, the highest I’ve ever seen on admission, with a extraordinarily low heart rate of 55, which I saw drop down to 51 after several hours of rest approaching dozing off. This all stabilized back to 127 over 76, with a heart rate of high sixties when I got off the gurney the next day. I still did have those weird wandering chest pains on the way out of the ER, tho. In the middle of the night that night, I had a brief experience of feeling a stabbing pain in middle of my chest, lasting just a second, which then zapped to the ends of one finger at the ends of both arms. Weird, but I was thankful it only lasted an instant. The next day I had a stress test and was essentially good. My pre-test BP was 117 over 63. The PA took me up to 100%, holding me at 155 BPM for five minutes, with only the comment that one trace looked like there could be a slight partial blockage. I was tired and winded but OK. Three days later, after warming up with 20 laps in a collegiate length pool, I did some 50 yd. sprints. The second or third one, I felt chest pains and a pain in the jaw which lasted less than a minute after I stopped, a slight back pain, and felt a bit dizzy. I did a few more easy laps then got out of the pool. Now I’m back to wandering, stinging chest pains, which are not severe but a bit annoying. I suppose I’m in for more tests now.

  11. Hi…it was wonderful meeting you the other day! Sure I would like the e-mail on what to do if you are in the ER clutching your chest….thank you!


  12. like to learn the five essential survival tools for when you do arrive to the ER with chest symptoms concerning for a heart attack, Please send them to me.

  13. I wish I had encountered this information BEFORE I had my heart attack. Although I was a long-time smoker, I had eaten a fairly healthy diet for many years. I was an Adele Davis fan decades ago when my kids were growing up, still have all her books, and her sound recommendations no doubt protected the kids as well as me from more serious harm. But the heart attack was a surprise.

    Along with the warnings about the dangers of the stent placement, I was also told that I would die without it. Not knowing any better, I accepted that as true. Now my stent and I are knee-deep in vegan, fat-free, raw-food, “heart-healthy” diet books. It’s very confusing, because I also have fibromyalgia, and everything I’ve read indicates that a low-carb anti-inflammatory diet with some healthy fat is the best way to fight that, and I’ve had good success controlling symptoms that way for several years. Now I’m eating fat-free, and my pain is back, my rosacea is returning with a vengeance, and I feel worn out and hungry all the time. I’d almost rather have another heart attack! (Okay, not really.)

    I’m in the middle of _Deep Nutrition_ and I just want to say thank you. I’m really looking forward to adding some things back into my diet that I’ve missed very much — things like butter and cheese and soup made with real bones. All this time I’ve been thinking about my grandmother, who cooked with lard and made chicken soup with chicken feet and served liver at least once a week, and lived to be 91, and I’ve been wondering about the wisdom of a diet without any meat or fat. (God, I want a cheese and spinach omelet cooked in butter!)

    My oldest son turned 40 today and was just complaining about joint pain and what a drag it is getting older. I’ll be giving him a copy of _Deep Nutrition_ for his birthday.

    Any additional information you can offer on healing arterial disease would be most appreciated.


  14. Hello Dr. Cate,

    I liked the article though I would have liked to see more advice on how to treat damaged arteries naturally.

    My mother has just been diagnosed with cerebral aneurysm. I don’t believe it has ruptured but the possibility of operating it is there. There is one more test to be done to see the aneurysm better. My mother has never drunk and smoke in her life. I can say that diet wise, she has never eaten junk, but she might have eaten a bit too many fats and maybe sugar. She also had a heart attack when she was only 48. Also, she is a bit on the overweight side without being obese though.

    Do you recommend any specific natural foods or teas that she could use to help strengthening her arteries and also clean them. I have read about green tea, garlic etc. and I know that physical exercise is recommended. But do you have any other suggestions?

    Is there a way to avoid surgery. I understand that if the aneurysm is big, they will have to operate no matter what and they only leave it if it is small. I don’t think my mother’s is small.

    Thanks so much,

  15. Dr. Cate, I enjoyed the article very much. Would appreciate any updated science on atherosclerosis reversal. I have stopped eating any grains, sugar or dairy (except for the odd piece of goat cheese) and converted to the Paleo diet consisting of organic grass fed beef, buffalo, free range chicken and eggs, vegetables, nuts, seeds, berries and some fruit. (Still have a glass of red wine each night). My weight has gone down 23 lbs. in 6 weeks from 213lbs to 190 lbs. and I feel amazing.

    1. Good for you. To reverse a disease, you have to understand it’s cause and unfortunately the standard view of fat clogging an artery is sorely out of date. We discuss the true cause of atherosclerosis in detail in Chapter 8 of Deep Nutrition, which will give you a very clear understanding of its reversal as well.

  16. Well folks I would like to email Dr. Cate however there doesnt seem to be a link for that purpose. if you are adding those concerned to a list for that purpose I would be pleased to be added to the list.
    Thank you Dr. for such timely information and God Bless.

  17. Tim
    Yes it will help vasculitis. Vasculitis is an inflammatory condition that may involve antibodies. The extent to which you can improve, and how fast, will depend in part on whether you have antibodies. If you do not, there will be faster improvement. Low fat diets tend to be high carb and are pro-inflammatory.

  18. Hello Dr Cate,
    do you think the diet you recommend would also help reverse Vasculitis? Most of the stuff I’ve found on the web describes how it is best treated with a low fat diet.

  19. Mary
    Claudication, or “bad circulation” in the legs will also reverse and exercise is key, so your training routine is going to be essential.

  20. Hi, again, Cate –
    Does the reversal process also apply to claudacation? I am 80 years old and very active, low Blood Pressure, Total cholesterol under 150 (good ratios). In spite of doing regular exercise (weight training & light cardio), I have had frequent cramping in legs and hands for the last ten years. Also ED. It’s only recently, however, that I have started switching from a low fat vegan diet to a Atkins style low carb program. I have cut out coffee, all wheat products, and added sugar. My daily complex carb intake is still probably over 100 grams, but I am working on reducing that. Protein every meal and tons of steamed veges. I am hoping this helps!
    Murray Crow

  21. Yes, I would like to see your comments re: But what if, God forbid, you do wind up in the ER clutching you chest in pain? What do you need to know to have an intelligent informed discussion with your treating physicians? If you would like to learn the five essential survival tools for when you do arrive to the ER with chest symptoms concerning for a heart attack, send me an email me and tell me so, and I just might make that the subject of my next post. Thank you!

  22. Hi Dr. Cate,

    Not sure how to e-mail you, but wanted to leave a comment to say…Yes! I would like to learn the five essential survival tools for what to do when you arrive to the ER with chest symptoms concerning for a heart attack.

    Thank you,


  23. Thanks Cate. No ED. At last test, I don’t take meds, HDL 3.2, LDL 3.1 (Friedewald) and Trig of 0.8 (all mmol/L) so I guess that’s all good. Will check out the Bruce protocol. Cleared for heavy exercise 18mo ago and going strong

  24. Enjoyed the book. Thanks for this post.

    How is one to know that one is making progress in improving one’s cardiovascular health? I’ve been working at it for two years since having an MI and having two lesions stented. Is it just a matter of faith or is there some objective assessment?

    1. How to know:
      1. The best test of cardiovascular health by far is exercise tolerance. The ability to go up to 10 METS on a Bruce protocol gives you a CV health score of 100%: it is the most reliable predictor of not dying from a heart attack. Want to do a Bruce Protocol at home on your treadmill? If you’ve been medically cleared to exercise, check out Wikipedia’s Bruce Protocol and follow the submaximal table till you’ve completed stage 3.
      2. Another functional test: ED. If you had that before, it should get better–and if your testosterone levels are normal the improvements will be more robust.
      3. Get your lipids tested off meds. If your HDL is over 50 (men) or 60 (women) and your triglycerides are under 150, that’s good. LDL should also be less than 3x HDL.

      These three are the mosts reliable and cheapest objective tests that anyone can do. There are a plethora of others: Calcium scores, ultrasound measurements, more expensive lipid tests. But none of these are as well studied as those I mentioned, so while they may be fun to do if you have extra cash burning a hole in your pocket, I don’t think they’re in any way essential.

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