skip to Main Content

FDA Officially Unconcerned that Crestor Causes Diabetes

Imagine a world where everyone is on powerful cholesterol-lowering drugs. Not just sick people. Everyone.

Astra Zeneca has imagined it, and now they’re going to see their dream come true. On December 16, the FDA announced their approval of Astra Zeneca’s cholesterol-lowering drug Crestor for use in people without high cholesterol despite the fact that a new study showed conclusively that the drug causes diabetes. By a vote of 12 to 4, the panel judged that even people at very low risk of heart disease should take the cholesterol medication anyway.

“I do think the diabetes problem is real, but I’m comforted by the fact that the drug works even in that patient group, so it’s very convincing,” said Michael Proschan, a statistician with the National Institutes of Health. In other words, even after Crestor gives you diabetes (or some other problem, see below), it may still cut your risk of certain types of heart disease, so why worry?


Fatburn Fix Saves Life of Type 2 Diabetic

I would like to thank you for literally saving my life. Back in February, I had to be hospitalized while on vacation in Phoenix with an A1C of 11% and had to start taking 2 types of insulin and 2 other meds. I read the Fatburn Fix in April, and followed the program to a tee, and I’m down by 15 pounds, 6.8 A1C, and only one once weekly diabetes medicine. Prior to reading the book, it was almost impossible for me to lose weight as a diabetic. 

Leontyne Tompkins

I feel free

For the last month, I have really been reading all labels on everything. I have completely remove those 8 oils you talk about. I must tell you, I feel great! I have more energy and I am now 197 lbs (have always been around 205 to 210lbs). I eat potatoes with real butter, grass fed steak, pasta with the right toppings. I eat everything! I seem to crave less sugar. I love it! 

Robert Kirkendall

I feel so much better

I had terrible aches and pains everywhere in my body, my hands, shoulders and knees. I feel so much better and the way I feel is motivating me every day! Thank you

Mike Deb Wootan Burcin

Better than ever

I am an anesthesiologist in Orlando and a huge fan of both of your books! I have been incorporating your principles for the last 10 months and feel that my health is better than ever.

Marnie Robinson, MD

My allergies disappeared

The biggest difference for me (and a surprising one) is that my allergies have almost completely disappeared! This is a big deal for me, because I’ve had allergies most of my life and they have often affected what I do which is a teaching music in [a public school district].  In general, I feel much better and have more consistent energy throughout the day.

Erica Turrell

Heart Palpitations have Stopped

I’ve lost 20+ pounds (also fasting 16-24 hours daily) and haven’t had palpitations except for one occasion — I had a mini bag of Fritos for the first time in July. And, I feel better now on a daily basis than I ever did all through college.

Mike Wright
Deep Nutrition and Fatburn Fix reader
Mitzi Wilkinson Champion

I’ve lost over 50 pounds

I’ve lost over 50 pounds. I’m 56 years old. Cutting processed food and unhealthy fats from my diet was one of the first things I did on my health recovery journey...I went cold turkey off the bad oils. Emptied my pantry into the trash and just started eating real food

Mitzi Wilkinson Champion

Knowledge I didn’t know I needed

Your Fatburn Fix book is amazing, my friend. Thank you! I’m an Functional Nutritional Therapy Practitioner and I know my stuff. This is the extra layer of knowledge I didn’t know I needed. Well done!

Jennifer Dillman
Fatburn Fix reader

Lost a solid 20 lbs and my bloodwork is great

I have lost a solid 20 lbs and my bloodwork (after 3 months of eating your way) was even better! I was metabolically healthy (per your book) before I read your book, but barely. Lowering my weight, sealed the deal! I have been talking about you and your book to anyone who will listen...Thank you for all you’ve done and what you continue to do! You are changing lives for the better!

Missy Cramer
FatBurn Fix reader

Lost 20 lbs I could never shed

I love your Fatburn Fix!  Has helped me so so much!  I have had the dreaded weight all my life - 20 or so pounds I could never shed.  I have lost that now. I only eat 2 meals a day lunch and dinner with a glass of milk or cappuccino around 4 to hold me over. No snacking and not bad oils.  It has been the key to unlocking my fatburn.  I work out in the am and believe I am burning fat for energy not from food!

Lauren Smith

I feel great

My waist is four inches smaller. I feel great and many of the minor aches and pains that I had (knees and lower back) are gone. Also, my muscle tone is amazing, even though I have not increased my workout routine.

Richard Janelle
Completed Dr Cate's online course
Kent Matthes

The go-to for strength and conditioning coaches

Whenever I advise my clients about eating to perform I go straight to what I have learned from Dr. Cate. Her book Deep Nutrition has become the go-to for strength and conditioning coaches across the country.

Kent Matthes
Major League Baseball Agent with WME Sports
Ken D Berry

Dismantles the lie

Dr. Cate dismantles the lie that seed oils are healthy, which may the biggest lie about nutrition and health because it’s so insidious.  

Ken D Berry, MD
Author of Lies My Doctor Told Me
Dr. Drew Pinsky

She knows the chemistry

Dr. Cate alerts us to the harms of seed oils and she’s convincing because she knows the chemistry better than anyone.

Dr. Drew Pinskey, MD
Globally recognized internal medicine and addiction medicine specialist, media personality, LoveLine Host, and New York Times bestselling author
Kelly Starrett

No one is better at communicating nutritional truth

Dr. Cate has had the single greatest impact on how we talk to people about fueling for both performance or durability. While we all are a little unique, the foundational principles of human nutrition are immutable. If you are looking to create a more durable, resilient body, no one is better at communicating nutritional truth than Dr. Cate.

Dr. Kelly Starrett
Physiotherapist coach and New York Times and Wall Street Journal bestselling author
Brian Lenkzes

Highly recommend The Fatburn Fix

Dr. Shanahan has had a significant impact on my practice of medicine. I am known as a Low Carb Doctor, but I never really appreciated the negative effects of processed seed oils on the health of my patients. I highly recommend The Fatburn Fix to my patients and have a loaner copy in my waiting room. It is amazing how quickly blood sugars and overall health improves with cutting seed oils. It is not just about the carbs!

Dr. Brian Lenkzes, MD
CEO of LowCarbMD San Diego, co-host of Low Carb MD Podcast and host of Life's Best Medicine Podcast
Chris Kaman

Respected in the sports world

Dr. Cate reordered my diet when I was with the L.A. Lakers, and the benefits, for me personally, were felt immediately and have served me to this day. I’ve come to take real food so seriously I started a small family farm. I know of no M.D./nutritionist more respected in the sports world than Dr. Cate Shanahan.

Chris Kaman
NBA Player
Mark Sisson

Brought seed oil issue front and center

Cate brought the seed oil issue front and center. Healthy fats matter. So much so that I created an entire product line to swap out bad fats with good.

Mark Sisson
Founding Father of the Primal/Paleo Movement
Dallas Hartwig

Optimal health starts with food

If you want to understand how optimal health starts with food, start with Dr. Cate. Her book Deep Nutrition leaves you with an appreciation of the profound relationship between our genes and the planet, inspiring us to be good shepherds of both.

Dallas Hartwig
Attribution author of The Whole 30
Dwight Howard

Helped me with endurance

Deep Nutrition really helped me with endurance. I started to feel better as a player. I was able to run more, I was able to be more active …and I just decided to keep going with it to this day.

Dwight Howard
NBA Player
Paul Grewal

Silver bullet for me

Dr Cate’s teachings helped me lose 60 pounds like it was nothing. It was like a silver bullet for me.

Paul Grewal, MD 
Dr Grewal Internal Medicine, MD, author of Genius Foods
Joesph Mercola

Radically improve your health…

Dr. Shanahan has provided a solid reference that deserves a place in the library of anyone who is seriously interested in nutrition. Her perspective on the vital role that healthy fat has in our diet is novel and, if implemented, can radically improve your health.

Dr. Joseph Mercola
Author of Fat for Fuel and Founder of Mercola.com
Dave Aspery

Pull up a chair…

I have based my work on the idea that getting the right kinds of healthy fats into your body and avoiding the worst fats is essential to optimal health. I've interviewed dozens of the world's top experts about this, and I know of no one who speaks more eloquently on this topic than Dr Cate. If she’s talking fats, pull up a chair. Take notes.

Dave Asprey
Author of the Bulletproof Diet

The key to unlocking my fatburn

I love your Fatburn Fix!  Has helped me so so much!  I have had the dreaded weight all my life - 20 or so pounds I could never shed.  I have lost that now. I only eat 2 meals a day lunch and dinner with a glass of milk or cappuccino around 4 to hold me over. No snacking and not bad oils.  It has been the key to unlocking my fatburn.  

Lauren Smith

Saved my life

I would like to thank you for literally saving my life. Back in February, I had to be hospitalized while on vacation in Phoenix with an A1C of 11% and had to start taking 2 types of insulin and 2 other meds. I read the Fatburn Fix in April, and followed the program to a tee, and I’m down by 15 pounds, 6.8 A1C, and only one once weekly diabetes medicine. 

Leontyne Tompkins

Tears of joy

 I'm crying tears of joy and appreciation for all you've done for me and my health! Without Deep Nutrition and Fatburn Fix, I would literally still be in the vicious cycle I'd been fighting all my life! In a nutshell - I am no longer a compulsive overeating addict suffering under the crushing 'thumb' of all food and alcohol.     

Penni Wicks

How Diabetic Retinopathy Impairs Vision
How you see the world with diabetic retinopathy

If you’ve been reading my blog, you probably aren’t surprised by this absurd determination. As I’ve said elsewhere, the intention of the drug companies is to market their products like Wrigley’s markets chewing gum: to sell to everyone, not just sick people. And the FDA often lends them a helping hand.

The December 16, 2009 declaration was made after the FDA completed a review of a large study published in 2008, known as the JUPITER study.

In designing the JUPITER study, Astra Zenica wanted to show that Crestor might benefit people without high cholesterol in order to expand Crestor’s potential customer base by an estimated 65 million people. So Astra Zenica enrolled people with normal cholesterol but high levels of body inflammation as measured by a protein called CRP, or C-reactive protein. Then they waited to see what would happen.

The study concludes that Crestor reduced the subjects’ risk of certain kinds of heart disease by 40%. But that’s not what the study actually shows—and the FDA knows it!

The people who make money selling Crestor designed and paid for the study, so of course it would be foolish to take any of these results at face value. But that’s exactly what the FDA does, assuming enough of us will be fooled by the pretense of oversight to make this whole charade profitable.

To give JUIPITER and other studies the appearance of legitimacy, drug companies have perfected the art of stacking the deck in their favor by a variety of methods. Basically, they cheat.

How drug companies cheat…

Firstly, they tend to pick the kinds of people likely to benefit from the drug, and exclude those likely to suffer side effects from entering their studies. In the case of JUPITER (as is the case with most cholesterol drug studies), by excluding anyone with heart failure or a history of cancer from participating, they reduce the number of people who suffer from the known propensity of Crestor to damage heart muscle cells and derange the immune system. (They don’t advertise that they did this so your doctor may have no idea that the drug has not been tested on people with these two common conditions.)

Secondly, they use statistical terms that don’t mean what most people (including doctors) think they mean, which brings us to that supposed 40%. Nobody’s risk was cut by 40%, only their relative risk was cut.

Huh?

The people enrolled in JUPITER were all at low risk of suffering a stroke or heart attack, with an average probability of 2.8 percent over the 1.9 years of the study. The drug cut their risk down to 1.6 percent. You and I would read that as a reduction of 1.4%. But applying the strange math of statistics, they can actually lie and get away with it, and they do so by comparing not the ABSOLUTE risk (1.4) but the RELATIVE risk (40 percent). Where does 40% come from? Simple: 2.8 is 40% more than 1.6, so the relative risk reduction is 40%.

Statistical manipulations are frequently employed by the authors of drug company-sponsored studies to make almost every drug seem far better than it really is.

The third way drug companies cheat is by pretending they don’t understand basic physiology.

Crestor Causes Diabetes, Diabetes Causes Heart Disease, Therefore Take Crestor to Prevent Heart Disease (???)

JUPTER showed that taking Crestor will INCREASE your relative risk of developing diabetes—by a whopping 29 percent over just 1.9 years. Over a longer period of time than 1.9 years, presumably a larger proportion of people would develop diabetes. Diabetes increases your risk of heart disease. And over all that time, many of those people who have Crestor to thank for their diabetes will also develop heart disease.

By the way, every doctor understands that diabetes increases your risk of heart disease. So where is the outpouring of protest by concerned physicians?

And by the way, every academic physician who has published a paper does understand the difference between relative risk and absolute risk. So where are the John’s Hopkins and Harvard intellectuals warning people about the misrepresentations of the facts?
scratch back

This apathy on the part of many MDs is a big reason that people are loosing faith in allopathic medicine, skipping important vaccines, and putting off the purchase of health insurance until after its already too late.

Diabetes not only increases your risk of heart attacks and strokes, but also of cancer, chronic musculoskeletal pain, dementia, and more. Crestor itself, by reducing your body’s ability to make isoprene units, directly increases your risk of all these things as well.

This increase in diabetes was the reason for the FDA’s mandatory review, but I think anyone who follows the news knows that the FDA is bought and sold and the review process is nothing more than window dressing serving to do little more than offer an excuse for more interviews and more free advertising for the supposed benefits of our latest wonder drug.

So should you get your CRP tested? Sure. If it’s high, that’s a good indication that the diet you are following is likely to make you sick. (CRP is also elevated when the immune system is highly active, as it is during infections and autoimmune disorders.) But if you ask your doctor if Crestor—or any other cholesterol-lowering medication—is “right for you?” keep in mind, he or she may be inclined to simply continue going along with whatever the FDA recommends.

If you care about your health, don’t let your doctor off the hook so easily. Ask why you’d want to take a pill that’s been proven to put you at risk of diabetes.

Dr. Cate

With over two decades of clinical experience and expertise in genetic and biochemical research, Dr. Cate can help you to reverse metabolic disease and reshape your body.

This Post Has 6 Comments

  1. I have been hit with both medication from a heart doctor to a hospital that give my husband the wrong medication. I nee to detoxi my body from these drug (Liptor and Crestar, )ect. I am try of truing the medical field with my life. How can I function it your body is not healthty.

  2. “In every medicine there is a little poisen” ~
    But perhaps just a little too much in the Statin class. There have been several recent studies that point out that fat is not the culprit. We are now learning that its carbs, high processed carbs that are in reality causing high trigs, which also lead to small dense cholesterol particles (the kind that penetrate artery walls and cause unstable plaques).
    I know several people who have benefited form a Paleo type diet (caveman) and even though their cholesterol may have even increased, their overall health has improved.

  3. Certainly Dr Cate is not saying that modern drugs do not save lives.

    She is pointing out that when science takes a back seat to marketing as with the Jupiter study the public’s faith in medicine falls — as it should.

    Drugs that cause diabetes for people who aren’t even at risk? When C-reactive protein is not even a valid surrogate endpoint? And the principal investigator of the Jupiter study holds a related patent? Please!

  4. to read this article,everyone is incompetent or in bed with drug companies which save our lives and give us the best standard of health since the creation of the earth, to read this article the average person would be mislead to believe that- everyone- 18,000 people were all picked so drug companies would make money and the FDA is made up of incompetence and only the author of this article is telling the truth. This articles fear mongering and makes the average person think you have a 29 percent chance of getting diabetes on Crestor, which is not the case, the author is playing with the numbers to try to make a name for themselves.
    Take your crestor, it is a good drug, minimal to no side effects and the most effective fat lowereing drug on the market. and i don’t work for the drug companies

    1. Thank you for pointing out a potential misunderstanding. Crestor does not cause an absolute risk of diabetes equalling 29 percent, but rather a 29 percent additional risk over whatever your risk would be off the drug. I hope you disclose this to your patients, Dr. Schwartz. But based on your authoritarian tone I suspect you just tell them “Tak your crestor, it is a good drug, minimal to no side effects and the most effective fat lowereing [sic] drug on the market”

      By the way, you might want to read the package insert because Crestor lowers cholesterol, not “fat,” and if you tell your patients the drug will lower their “fat” you are implying Crestor helps with weight loss, which is unsubstantiated.

    2. Anyone reading this might be tempted to assume that doctors and drug companies are responsible for the best standard of health since the creation of the earth. One would do better to thank the sewage workers and those responsible for the supply of clean water.

Leave a Reply

Back To Top
Search