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Statin Side Effects Slowing You Down? Why your doctor may not be able to help.

A new plan unveiled this week by the Department of Health and Human Services will make it more difficult for a patient to have an open and frank discussion with his doctor about the potential side effects of statin medications.

If you ask about statin side effects, your doctor may be distracted

It’s no secret that statins, taken to reduce your risk of heart attack and stroke, can have serious side effects (that include developing diabetes); simply read the package insert. It’s not unusual that, when reviewing a new patient’s previous charts, I see they have experienced symptoms potentially attributable to their statin prescription(s). Sometimes the nurses’ notes even document that the patient expressed concern that their symptoms might be the side effects of their statin medication(s). Often, however, the record shows that their doctor’s response was to simply scribble out another prescription to treat the new symptoms.

When you talk “privately” with your doctor, is someone else in the room with you?

Few people know that when a patient has a private talk in the exam room with his personal health care provider, he is often not—as much as he might like to believe—having a one-on-one conversation. Any time you are on a medication you suspect may be hurting you, and you go through the “ask your doctor if you are experiencing” routine, the answers you get may depend on what your insurance company wants your doctor to say.

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Kobe Bryant

It helped. I feel great.

"It’s helped. I feel great."

Kobe Bryant
NBA baskeball player
megyn kelly

This has been life changing

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Megyn Kelly
Jesse Watters

Life changing

Deep Nutrition changed my life.

Jesse Watters
Fox News Primetime host

Saved my life

I would like to thank you for literally saving my life. Back in February, I had to be hospitalized while on vacation in Phoenix with an A1C of 11% and had to start taking 2 types of insulin and 2 other meds. I read the Fatburn Fix in April, and followed the program to a tee, and I’m down by 15 pounds, 6.8 A1C, and only one once weekly diabetes medicine. Prior to reading the book, it was almost impossible for me to lose weight as a diabetic. 

Leontyne Tompkins

I feel free

For the last month, I have really been reading all labels on everything. I have completely remove those 8 oils you talk about. I must tell you, I feel great! I have more energy and I am now 197 lbs (have always been around 205 to 210lbs). I eat potatoes with real butter, grass fed steak, pasta with the right toppings. I eat everything! I seem to crave less sugar. I love it! 

Robert Kirkendall

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I had terrible aches and pains everywhere in my body, my hands, shoulders and knees. I feel so much better and the way I feel is motivating me every day! Thank you

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The biggest difference for me (and a surprising one) is that my allergies have almost completely disappeared! This is a big deal for me, because I’ve had allergies most of my life and they have often affected what I do which is a teaching music in [a public school district].  In general, I feel much better and have more consistent energy throughout the day.

Erica Turrell

Heart Palpitations have Stopped

I’ve lost 20+ pounds (also fasting 16-24 hours daily) and haven’t had palpitations except for one occasion — I had a mini bag of Fritos for the first time in July. And, I feel better now on a daily basis than I ever did all through college.

Mike Wright
Deep Nutrition and Fatburn Fix reader
Mitzi Wilkinson Champion

I’ve lost over 50 pounds

I’ve lost over 50 pounds. I’m 56 years old. Cutting processed food and unhealthy fats from my diet was one of the first things I did on my health recovery journey...I went cold turkey off the bad oils. Emptied my pantry into the trash and just started eating real food

Mitzi Wilkinson Champion

Knowledge I didn’t know I needed

Your Fatburn Fix book is amazing, my friend. Thank you! I’m an Functional Nutritional Therapy Practitioner and I know my stuff. This is the extra layer of knowledge I didn’t know I needed. Well done!

Jennifer Dillman
Fatburn Fix reader

Lost a solid 20 lbs and my bloodwork is great

I have lost a solid 20 lbs and my bloodwork (after 3 months of eating your way) was even better! I was metabolically healthy (per your book) before I read your book, but barely. Lowering my weight, sealed the deal! I have been talking about you and your book to anyone who will listen...Thank you for all you’ve done and what you continue to do! You are changing lives for the better!

Missy Cramer
FatBurn Fix reader

Lost 20 lbs I could never shed

I love your Fatburn Fix!  Has helped me so so much!  I have had the dreaded weight all my life - 20 or so pounds I could never shed.  I have lost that now. I only eat 2 meals a day lunch and dinner with a glass of milk or cappuccino around 4 to hold me over. No snacking and not bad oils.  It has been the key to unlocking my fatburn.  I work out in the am and believe I am burning fat for energy not from food!

Lauren Smith

I feel great

My waist is four inches smaller. I feel great and many of the minor aches and pains that I had (knees and lower back) are gone. Also, my muscle tone is amazing, even though I have not increased my workout routine.

Richard Janelle
Completed Dr Cate's online course
Kent Matthes

The go-to for strength and conditioning coaches

Whenever I advise my clients about eating to perform I go straight to what I have learned from Dr. Cate. Her book Deep Nutrition has become the go-to for strength and conditioning coaches across the country.

Kent Matthes
Major League Baseball Agent with WME Sports
Ken D Berry

Dismantles the lie

Dr. Cate dismantles the lie that seed oils are healthy, which may the biggest lie about nutrition and health because it’s so insidious.  

Ken D Berry, MD
Author of Lies My Doctor Told Me
Dr. Drew Pinsky

She knows the chemistry

Dr. Cate alerts us to the harms of seed oils and she’s convincing because she knows the chemistry better than anyone.

Dr. Drew Pinskey, MD
Globally recognized internal medicine and addiction medicine specialist, media personality, LoveLine Host, and New York Times bestselling author
Kelly Starrett

No one is better at communicating nutritional truth

Dr. Cate has had the single greatest impact on how we talk to people about fueling for both performance or durability. While we all are a little unique, the foundational principles of human nutrition are immutable. If you are looking to create a more durable, resilient body, no one is better at communicating nutritional truth than Dr. Cate.

Dr. Kelly Starrett
Physiotherapist coach and New York Times and Wall Street Journal bestselling author
Brian Lenkzes

Highly recommend The Fatburn Fix

Dr. Shanahan has had a significant impact on my practice of medicine. I am known as a Low Carb Doctor, but I never really appreciated the negative effects of processed seed oils on the health of my patients. I highly recommend The Fatburn Fix to my patients and have a loaner copy in my waiting room. It is amazing how quickly blood sugars and overall health improves with cutting seed oils. It is not just about the carbs!

Dr. Brian Lenkzes, MD
CEO of LowCarbMD San Diego, co-host of Low Carb MD Podcast and host of Life's Best Medicine Podcast
Chris Kaman

Respected in the sports world

Dr. Cate reordered my diet when I was with the L.A. Lakers, and the benefits, for me personally, were felt immediately and have served me to this day. I’ve come to take real food so seriously I started a small family farm. I know of no M.D./nutritionist more respected in the sports world than Dr. Cate Shanahan.

Chris Kaman
NBA Player
Mark Sisson

Brought seed oil issue front and center

Cate brought the seed oil issue front and center. Healthy fats matter. So much so that I created an entire product line to swap out bad fats with good.

Mark Sisson
Founding Father of the Primal/Paleo Movement
Dallas Hartwig

Optimal health starts with food

If you want to understand how optimal health starts with food, start with Dr. Cate. Her book Deep Nutrition leaves you with an appreciation of the profound relationship between our genes and the planet, inspiring us to be good shepherds of both.

Dallas Hartwig
Attribution author of The Whole 30
Dwight Howard

Helped me with endurance

Deep Nutrition really helped me with endurance. I started to feel better as a player. I was able to run more, I was able to be more active …and I just decided to keep going with it to this day.

Dwight Howard
NBA Player
Paul Grewal

Silver bullet for me

Dr Cate’s teachings helped me lose 60 pounds like it was nothing. It was like a silver bullet for me.

Paul Grewal, MD 
Dr Grewal Internal Medicine, MD, author of Genius Foods
Joesph Mercola

Radically improve your health…

Dr. Shanahan has provided a solid reference that deserves a place in the library of anyone who is seriously interested in nutrition. Her perspective on the vital role that healthy fat has in our diet is novel and, if implemented, can radically improve your health.

Dr. Joseph Mercola
Author of Fat for Fuel and Founder of
Dave Aspery

Pull up a chair…

I have based my work on the idea that getting the right kinds of healthy fats into your body and avoiding the worst fats is essential to optimal health. I've interviewed dozens of the world's top experts about this, and I know of no one who speaks more eloquently on this topic than Dr Cate. If she’s talking fats, pull up a chair. Take notes.

Dave Asprey
Author of the Bulletproof Diet

The key to unlocking my fatburn

I love your Fatburn Fix!  Has helped me so so much!  I have had the dreaded weight all my life - 20 or so pounds I could never shed.  I have lost that now. I only eat 2 meals a day lunch and dinner with a glass of milk or cappuccino around 4 to hold me over. No snacking and not bad oils.  It has been the key to unlocking my fatburn.  

Lauren Smith

Saved my life

I would like to thank you for literally saving my life. Back in February, I had to be hospitalized while on vacation in Phoenix with an A1C of 11% and had to start taking 2 types of insulin and 2 other meds. I read the Fatburn Fix in April, and followed the program to a tee, and I’m down by 15 pounds, 6.8 A1C, and only one once weekly diabetes medicine. 

Leontyne Tompkins

> Tears of joy

 I'm crying tears of joy and appreciation for all you've done for me and my health! Without Deep Nutrition and Fatburn Fix, I would literally still be in the vicious cycle I'd been fighting all my life! In a nutshell - I am no longer a compulsive overeating addict suffering under the crushing 'thumb' of all food and alcohol.     

Penni Wicks


It works like this. Right now, a small portion of the money you pay for health insurance is allocated to your doctor through a system of evaluations called “pay-for-performance.” When the health insurance company agrees with what your doctor is doing, the doctor is paid better. When the health insurance company disagrees, your doctor is financially penalized.

Pay for Performance: How corporations get doctors to do what’s good for  you business

Insurance companies argue that pay-for-performance helps ensure that physicians make recommendations in the best interest of patients, and that these financial incentives (or penalties, depending on your point of view) help elevate “standard of care.” Whether or not one agrees with this, it’s clear that a more accurate term for the policy would be “pay for compliance,” and that such policies are likely to influence what your doctor is telling you. That is, after all, why these incentive policies were created—to influence physician care.

But there is at least one potentially serious side effect from insurance companies prescribing physicians’ recommendations: By incentivizing your doctor to make a recommendation he or she might not have made without the threat of financial penalty (or the promise of financial reward), insurance companies have placed themselves squarely between you and your doctor, intruding on this most sacred of relationships. With this new Department of Health initiative, whatever distractions that financial reward creates in your doctor’s mind as he listens to what you are saying and makes decisions about your future, that influence is about to grow much louder. The insurance companies will no longer merely be whispering in your doctor’s ear. They’ll now be “guiding” his recommendations through a bullhorn.

And this is why it has become especially important to ask him or her how likely it is that the drugs you take will actually help you, and to demand a lucid and detailed answer.

It’s also a good idea to get a second opinion, perhaps from a book

If you are familiar with my books, you know I’ve combed through a staggering amount of research and have yet to uncover a shred of compelling evidence tying LDL cholesterol to heart attacks. And if you’ve read Dr. Atkins, Gary Taubes, Mark Sisson, Robb Wolf and other nutrition luminaries, you know they have drawn the same conclusion: No solid evidence indicts cholesterol as the cause of heart disease. A new book by a cardiologist, out just last month, is joining the discussion, and it’s already a best-seller (Wheat Belly by Dr. William Davis). The gears of the anti-cholesterol machinery are slowly seizing up.

If you’ve read my books, you also already know that the stuff in our bloodstream that causes heart attacks is not happy normal cholesterol in happy normal LDL or HDL, but oxidized lipoprotein particles that became oxidized from a diet high in sugar and trans fat and lacking in nutrients. This assertion is not controversial; all lipid specialists agree. Currently though, I’m sorry to say, we have no test to measure just how many oxidized lipoprotein particles you have in your bloodstream. So we fudge it; we call LDL “bad cholesterol.” And for the giants of the pharmaceutical industry, that way of thinking about cholesterol works just fine: “Got bad cholesterol? No problem. We’ve a drug for that. And we pay our doctors in such a way that they forget that, like any other drug, statins have side effects, too.”

So are statin drugs “right for you,” or not?

A good way to determine how likely a drug is going to help is through a statistic called the “number needed to treat,” or NNT for short. If the NNT is low, say 5 or 10, that means that only 5 or 10 people just like you have to take the drug to prevent the occurrence of, say, a single heart attack.

The average person on a statin has a 1/100 chance that it will benefit them by preventing a heart attack or stroke. There is also a very good chance it will cause harm, but details are scarce because those kinds of studies are hard to fund and even harder to publish.

Statistics show that the NNT for statins is much higher than you might think, particularly given all the hype about how important they are for your health. The lowest reported NNT is 30, in male smokers who have already had one heart attack. For the average person with no history of heart attack, who doesn’t smoke, and who doesn’t have diabetes, it’s over 100.

Here’s an article that describes the problem:

“Another serious problem with the way the results are presented [to your doctor] is that the reader is often not told the number needed to treat (NNT) for one patient to benefit. The NNTs range from around 30 in the 4S and LIPID trials to over 100 in the primary prevention trials. But this is not the information that patients are likely to be given; instead, they will be told that they will reduce their risk of death by about 30%. Presenting information to patients in the form of relative risk will much increase their receptiveness to taking the drug.”

There’s another important number you want your doctor to be able to tell you: the number needed to harm. Unfortunately, because not too many drug companies are fond of funding research like this, there are precious few statistics published about the number of patients harmed by statins. One example I did find is for renal failure in women: the number needed to harm is only 434. That’s one side effect. Another is the development of diabetes: that’s 498. Cancer may need to be included as a side effect because in one study that was stopped early, The Effect of Pravistatin on Coronary Events after MI in Patients with Average Cholesterol Levels NEJM 355:1001-1009, 1996, 14 women on a statin developed a recurrence of their breast cancer compared to only 1 on the placebo. (The cancer association was much stronger than the effect of premarin on breast cancer, and that statistic led to a storm of media coverage.)

Statins can also cause severe liver dysfunction. Number needed to harm: 136. And cataracts: NNH=32!! You get the point.

A recent article in American Family Physician puts my gripe about misinformation rather well:

“With a NNT above 75, a number needed to harm would be helpful in determining if we should prescribe these medications to our patients.

It would be interesting to see if a patient’s decision whether or not to take the drug was influenced by using one of the following statements: ‘This drug will decrease your chance of dying by 12 percent.’ Or, ‘Out of the 167 patients that take this pill for the next four years, one patient will not die who would have if he or she had not taken the drug, but 166 will take the medicine and get no benefit, and may be harmed.’

There is a big difference between relative and absolute risk reductions. Conveying the NNT to our colleagues and patients provides a more accurate assessment of the effectiveness of a drug, and might help physicians and patients make more informed decisions.”

Statins can help some people, some of the time

The oxidized-lipoprotein-particle reality I mentioned above is the reason why the average person with high cholesterol is actually a teensy bit more likely to have a heart attack than the average person without high cholesterol. They are more likely because they have more particles vulnerable to oxidation, but only that teensy bit more likely, and that is only true if one is on the average (pro-inflammatory) diet. Therefore statin drugs are only a teensy bit likely to help the average person (who has not already had a heart attack, smokes, or has uncontrolled diabetes) on the average diet.

I have to say this next bit by way of disclaimer, but it’s also true: if I were your doctor, I would only stop these medications after sitting down with you and asking enough questions to get a realistic assessment of your risk of heart attack. As an essential part of your care, I would provide you with nutrition advice that would make you virtually heart attack proof by protecting your LDL (and other lipoproteins) from harmful oxidation events.

Unfortunately, though the diet I advise may make you virtually heart attack proof, if it fails to get your LDL number down to where your insurance company thinks it needs to be, I will be financially penalized.

On a positive note, if I may quote Nan from TrueBlood, my lastest favorite show, “There are factions inside the regime who have never been completely on board with the current agenda.” What I’m saying is, there are still doctors who will, believe it or not, refuse to play the pay-for-performance game—and take a financial hit for doing so. And there are hospitals and medical centers who still encourage doctors to keep their patients fully informed. Not sort of informed. Or “informed” in quotes—informed only so far as your insurance company wants you to be—but informed. Not many, but their numbers are growing daily.

That’s right. The sanctity of the patient-doctor relationship is not without its defenders. I’m talking about good doctors, good hospitals and knowledgable, conscientious patients who want to know what their trusted family physician really thinks.

In other words, people like you.

Check out these links for a good doctor in your area:

And this link is to a list of articles by the author of Wheat Belly, who is that rarest of animals a cardiologist who has a balanced view of the utility of statins:

With over two decades of clinical experience and expertise in genetic and biochemical research, Dr. Cate can help you to reverse metabolic disease and reshape your body.

Please note: Please do not share personal medical information in a comment on our posts. It will be deleted due to HIPAA regulations.

This Post Has 8 Comments

  1. Thanks Dr. Cate. Very informative blog! In my case though, I’ve had type one diabetes for 44 years and had by=pass surgery 3 years ago. How do I determine if I really need to be on statins or not? I have been on a low carb/complex carb diet with low animal protein for a while now. This is a very confusing topic.



    1. Gary you are one of the millions of Americans learning about this topsy turvy world of fats and suddenly finding themselves caught between their cardiologist and a hard place. You are unlikely to find a cardiologist who is willing to consider stopping a statin, now that you’ve had surgery. If you never actually had a heart attack and did not have heart failure, you may be able to argue that the evidence for the bypass benefitting you was limited and now you are concerned about further deepening the damage done by the continuation of a statin.

      In chapter 8 of Deep Nutrition I describe the great leap it took for me to open my eyes to the reality of what really causes heart disease, and therefore what should be done about it. That chapter should greatly help your understanding of what to do.

  2. Dr. Cate,
    Is there any Dr. in Manchster who thinks as You do? If so, name please. You are in total agreement with the big boys i.e.Jonathan Wright, Bruce West, Robert Rowen, Frank Schallenberger etc. who are all on the west coast. Now we add Cate Shanahan to the list. Please don’t change and succumb to big pharma. Thanks again for treating us while you were here. Regards,
    Al & Polly!

  3. Hello Dr Cate! I bought your book two weeks ago after listening to your Underground Wellness podcast. My boyfriend and I have been eating healthier over the past months, getting really great improvements in our moods and energy levels from getting rid of sugar and wheat. We were considering transitioning to Paleo but thought we would really struggle to also stop eating dairy, legumes and all grains. After listening to you on the podcast I bought Deep Nutrition on Kindle and devoured it in three days. It made me so excited to start the diet changes- not Paleo but traditional!

    We cooked our first organic grass-fed lamb leg roast last weekend- five hours in the oven! Tasted like heaven and we had leftovers for the next two nights as well. Am kicking myself I didn’t stop my boyfriend from throwing out the bone when he went and did the washing up. We do have another leg in the freezer though and he now knows all bones are to be kept for broth. This weekend I’m going to do a whole organic roast chicken in our slowcooker, and make some broth with those bones. I have a problem with pain in my knee when I run and am hoping the glucosamines might improve things. I am working up to trying liver, I’m still slightly queasy on the idea but am gaining courage when I think about how good it will be for me. Just need the right recipe. This week the only grains I have eaten have been sprouted quinoa, I even made some essene bread with it (need a bit more time to experiment with it I think). I am eating lentils and beans, we found an organic grocer selling unpasteurised butter and are frying our morning eggs and bacon in it. I am eating whole milk yoghurt first thing in the morning. I am snacking on nuts and cottage cheese and lupini beans.

    I am SO SATISFIED by the food I am eating!!!! This is so huge for me, as I am- well WAS that person who is ALWAYS HUNGRY even if I’ve just eaten. I’ve been reading through your blog here too and your May entry about how much carbohydrates we ‘need’ each day has made me feel safe to pretty much dump starchy carbs altogether- which have always made me feel fuzzy headed and hungry and BLOATED. I just didn’t see how I could be without them as I craved them and in fact it made me doubt whether I could maintain Paleo, because Paleo disallows legumes and I thought I couldn’t lose both. When I’m having a meat or bean meal with salads and veggies my stomach is staying pretty flat- I never thought I could have a contendedly full stomach without it puffing out!

    I wanted to ask if you and your publisher would consider enabling Deep Nutrition for sharing on Kindle devices. I wish I had bought a hard copy of the book because I want my parents and sister to read it; I’m also really keen to have two members of my bookclub read it as they are trying to get pregnant and I know they (and their future babies) would benefit so much from the info in Deep Nutrition. They wouldn’t seek the book out on their own because the information is just too diametrically opposed to the mainstream ‘healthy eating’ propoganda they have been bombarded with. But I have piqued their interest because they could see how adamant I was and as I explained some of the science and logic of your book. I said I would see I could share it with them via their Kindles, but discovered it was not enabled. While it might seem that authors and publishers would lose out on potential sales by enabling lending, I wanted to suggest that for a book such as yours the lending program (which I understand allows lending to up to six people from one kindle book purchase) has fantastic potential spread your influence and message and reach people who wouldn’t ordinarily be inclined to pick it up on their own but would read it if it was loaned from a friend.

    Thankyou so much for writing this book! Food Rules is next on my reading list, and I’m so excited to hear you are now writing the TRIM book, all my very best :o)

  4. Josh
    Me too. But I do know a few good men and women in the business, and I like to think our numbers will grow and our patients will flourish.

  5. Awesome post.

    To be honest, the direction modern medicine is going really scares me. It’s hard to say if we’ll actually see a paradigm shift in the near future, or if things will get worse before they’ll get better. On one hand it’s encouraging to see people like Robb Wolf and Mark Scisson make it somewhat mainstream, but “new plans” like this make things seem a bit more gloomy.


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