Overeating is Bad for Mitochondria: Calories Count, PUFA Calories Count More
We often overlook the fact that simply overeating puts a stress on the system (and PUFA-rich seed oils are the worst). I think we should include a fourth macronutrient: time between meals. The longer you can go without a meal or a snack or a beverage other than water, the healthier your mitochondria will be.