Is the calorie-free sweetener erythritol safe? The FDA did not evaluate long-term use, and new research suggests it may cause blood clots in people with high blood pressure and other risk factors.
Statisticians Can Easily Mislead Doctors About Statin (or any) Drug Safety
Doctors don’t go to medical school to become expert at interpreting statistics. Yet most of the articles that tell us how safe drugs might be rely on complex statistical analyses that go far beyond what I learned in my one credit course on Statistics for Medical Practitioners. For the most part, doctors have to take the word of the statisticians on whether a drug has a given benefit or harm.
An example is a recent Lancet review article has been hailed as the “definitive” summary of the potential risks versus potential harms of statin drugs. The authors conclude that most of the side effects we’ve thought statins had are actually nonexistent. They predict just 2 adverse events per 15 cases of heart attack or stroke prevented, and make rather strong statements about doctors not prescribing statins often enough.
A couple of folks I respect have pointed out that the authors have long served as apologists for the statin industry. In my video critique of the Lancet article I discuss Malcolm Kendrick, and HealthInsightUK.
My concern about this particular article is that, as far as being the last word on risk versus harm, it’s seriously flawed by failure to include ALL the common side effects in the analysis. Some side effects simply weren’t discussed, like heart failure. But most side effects were dismissed based on the results of randomized controlled trials. However, a little-known stage of most such trials called the “run-in” or “wash out” period, can be used to screen out massive numbers of study subjects. I believe that this little trick is often used to sway the results in favor of a given drug.
This article is continued below...(scroll down)
It helped. I feel great.
"It’s helped. I feel great."
NBA baskeball player
This has been life changing
"Let me tell you this has been life-changing. I have all of her books, in audible and ebooks! I have gotten rid of all the hateful 8 oils. I have trained my body to eat its own previously toxic body fat. Download that pod it's a game changer!"
Broadcaster / The Megyn Kelly Show
Deep Nutrition changed my life.
Fox News Primetime host
Saved my life
I would like to thank you for literally saving my life. Back in February, I had to be hospitalized while on vacation in Phoenix with an A1C of 11% and had to start taking 2 types of insulin and 2 other meds. I read the Fatburn Fix in April, and followed the program to a tee, and I’m down by 15 pounds, 6.8 A1C, and only one once weekly diabetes medicine. Prior to reading the book, it was almost impossible for me to lose weight as a diabetic.
I feel free
For the last month, I have really been reading all labels on everything. I have completely remove those 8 oils you talk about. I must tell you, I feel great! I have more energy and I am now 197 lbs (have always been around 205 to 210lbs). I eat potatoes with real butter, grass fed steak, pasta with the right toppings. I eat everything! I seem to crave less sugar. I love it!
I feel so much better
I had terrible aches and pains everywhere in my body, my hands, shoulders and knees. I feel so much better and the way I feel is motivating me every day! Thank you
Mike Deb Wootan Burcin
Better than ever
I am an anesthesiologist in Orlando and a huge fan of both of your books! I have been incorporating your principles for the last 10 months and feel that my health is better than ever.
Marnie Robinson, MD
My allergies disappeared
The biggest difference for me (and a surprising one) is that my allergies have almost completely disappeared! This is a big deal for me, because I’ve had allergies most of my life and they have often affected what I do which is a teaching music in [a public school district]. In general, I feel much better and have more consistent energy throughout the day.
Heart Palpitations have Stopped
I’ve lost 20+ pounds (also fasting 16-24 hours daily) and haven’t had palpitations except for one occasion — I had a mini bag of Fritos for the first time in July. And, I feel better now on a daily basis than I ever did all through college.
Deep Nutrition and Fatburn Fix reader
I’ve lost over 50 pounds
I’ve lost over 50 pounds. I’m 56 years old. Cutting processed food and unhealthy fats from my diet was one of the first things I did on my health recovery journey...I went cold turkey off the bad oils. Emptied my pantry into the trash and just started eating real food
Mitzi Wilkinson Champion
Knowledge I didn’t know I needed
Your Fatburn Fix book is amazing, my friend. Thank you! I’m an Functional Nutritional Therapy Practitioner and I know my stuff. This is the extra layer of knowledge I didn’t know I needed. Well done!
Fatburn Fix reader
Lost a solid 20 lbs and my bloodwork is great
I have lost a solid 20 lbs and my bloodwork (after 3 months of eating your way) was even better! I was metabolically healthy (per your book) before I read your book, but barely. Lowering my weight, sealed the deal! I have been talking about you and your book to anyone who will listen...Thank you for all you’ve done and what you continue to do! You are changing lives for the better!
FatBurn Fix reader
Lost 20 lbs I could never shed
I love your Fatburn Fix! Has helped me so so much! I have had the dreaded weight all my life - 20 or so pounds I could never shed. I have lost that now. I only eat 2 meals a day lunch and dinner with a glass of milk or cappuccino around 4 to hold me over. No snacking and not bad oils. It has been the key to unlocking my fatburn. I work out in the am and believe I am burning fat for energy not from food!
I feel great
My waist is four inches smaller. I feel great and many of the minor aches and pains that I had (knees and lower back) are gone. Also, my muscle tone is amazing, even though I have not increased my workout routine.
Completed Dr Cate's online course
The go-to for strength and conditioning coaches
Whenever I advise my clients about eating to perform I go straight to what I have learned from Dr. Cate. Her book Deep Nutrition has become the go-to for strength and conditioning coaches across the country.
Major League Baseball Agent with WME Sports
Dismantles the lie
Dr. Cate dismantles the lie that seed oils are healthy, which may the biggest lie about nutrition and health because it’s so insidious.
Ken D Berry, MD
Author of Lies My Doctor Told Me
She knows the chemistry
Dr. Cate alerts us to the harms of seed oils and she’s convincing because she knows the chemistry better than anyone.
Dr. Drew Pinskey, MD
Globally recognized internal medicine and addiction medicine specialist, media personality, LoveLine Host, and New York Times bestselling author
No one is better at communicating nutritional truth
Dr. Cate has had the single greatest impact on how we talk to people about fueling for both performance or durability. While we all are a little unique, the foundational principles of human nutrition are immutable. If you are looking to create a more durable, resilient body, no one is better at communicating nutritional truth than Dr. Cate.
Dr. Kelly Starrett
Physiotherapist coach and New York Times and Wall Street Journal bestselling author
Highly recommend The Fatburn Fix
Dr. Shanahan has had a significant impact on my practice of medicine. I am known as a Low Carb Doctor, but I never really appreciated the negative effects of processed seed oils on the health of my patients. I highly recommend The Fatburn Fix to my patients and have a loaner copy in my waiting room. It is amazing how quickly blood sugars and overall health improves with cutting seed oils. It is not just about the carbs!
Dr. Brian Lenkzes, MD
CEO of LowCarbMD San Diego, co-host of Low Carb MD Podcast and host of Life's Best Medicine Podcast
Respected in the sports world
Dr. Cate reordered my diet when I was with the L.A. Lakers, and the benefits, for me personally, were felt immediately and have served me to this day. I’ve come to take real food so seriously I started a small family farm. I know of no M.D./nutritionist more respected in the sports world than Dr. Cate Shanahan.
Brought seed oil issue front and center
Cate brought the seed oil issue front and center. Healthy fats matter. So much so that I created an entire product line to swap out bad fats with good.
Founding Father of the Primal/Paleo Movement
Optimal health starts with food
If you want to understand how optimal health starts with food, start with Dr. Cate. Her book Deep Nutrition leaves you with an appreciation of the profound relationship between our genes and the planet, inspiring us to be good shepherds of both.
Attribution author of The Whole 30
Helped me with endurance
Deep Nutrition really helped me with endurance. I started to feel better as a player. I was able to run more, I was able to be more active …and I just decided to keep going with it to this day.
Silver bullet for me
Dr Cate’s teachings helped me lose 60 pounds like it was nothing. It was like a silver bullet for me.
Paul Grewal, MD
Dr Grewal Internal Medicine, MD, author of Genius Foods
Radically improve your health…
Dr. Shanahan has provided a solid reference that deserves a place in the library of anyone who is seriously interested in nutrition. Her perspective on the vital role that healthy fat has in our diet is novel and, if implemented, can radically improve your health.
Dr. Joseph Mercola
Author of Fat for Fuel and Founder of Mercola.com
Pull up a chair…
I have based my work on the idea that getting the right kinds of healthy fats into your body and avoiding the worst fats is essential to optimal health. I've interviewed dozens of the world's top experts about this, and I know of no one who speaks more eloquently on this topic than Dr Cate. If she’s talking fats, pull up a chair. Take notes.
Author of the Bulletproof Diet
The key to unlocking my fatburn
I love your Fatburn Fix! Has helped me so so much! I have had the dreaded weight all my life - 20 or so pounds I could never shed. I have lost that now. I only eat 2 meals a day lunch and dinner with a glass of milk or cappuccino around 4 to hold me over. No snacking and not bad oils. It has been the key to unlocking my fatburn.
Saved my life
I would like to thank you for literally saving my life. Back in February, I had to be hospitalized while on vacation in Phoenix with an A1C of 11% and had to start taking 2 types of insulin and 2 other meds. I read the Fatburn Fix in April, and followed the program to a tee, and I’m down by 15 pounds, 6.8 A1C, and only one once weekly diabetes medicine.
> Tears of joy
I'm crying tears of joy and appreciation for all you've done for me and my health! Without Deep Nutrition and Fatburn Fix, I would literally still be in the vicious cycle I'd been fighting all my life! In a nutshell - I am no longer a compulsive overeating addict suffering under the crushing 'thumb' of all food and alcohol.
View my video critique of the Lancet article here, and let me know what you think. Do you believe doctors should also consider the potential harms from statin side effects that I review in the video, do you think they are irrelevant like the Lancet article claims?
This Post Has 2 Comments
I had 2 stents inserted in my Heart in July 2016 at age 65. I was a heavy smoker for 50 yrs. I’ve since quit. My cholesterol was ‘normal’ range at the time and has never been high by any standard. I was prescribed a daily statin, to be taken “forever”. At NO time was I told about side effects. The Doctor who prescribed the statin had my complete medical history, which includes Charcotte Marie Tooth Disease (CMT), a peripheral neuropathy. A short time later I awoke to a very swollen knee and could not move my leg an inch, in any direction. I had been experiencing very painful cramps in my toes and the arches of my feet and in my calves. My hands were cramping very badly. I assumed it was my CMT getting worse. Turns out it wasn’t. After about 18 hrs of being unable to move (I had pee’d into a couple of empty water bottles) I called the Fire Department to come and open my apartment door, so help could enter. Over the next several months this happened 3 more times but someone now had a key to my door. It cost me several hundred dollars for ‘home care’. At NO time did my GP or Cardio guy suggest the statin was my problem. I was experiencing very troubling memory problems. I accidentally came upon a short video on YouTube by MIT scientist Raymond Francis, which started me on a 30 hr probe about statins. I quit taking my Lipitor!! Within 24 hrs the cramps stopped and my memory started to improve. Once I found out that I did NOT have heart disease and had a strong Heart muscle, and learned about what that medication was for, I knew I had made the right decision. All the Cardio guy would say was that NONE of my medications would cause me ANY problems and I’d likely DIE without them. Any Doctor who would say that should be in the unemployment line. The whole “LDL is BAD for you” line is total BS! It does sell billions of little statin pills. I was believing that this pill was all that stood between me and certain death. There is more to this but I won’t put that info online. Be happy to discuss with ‘Dr Cate’ anytime. I apparently experienced something that was unprecedented.
Another form of “fake news.”
Turns out, you have to learn how to “read between the lines” and do your own research from multiple sources around the world, all just a few mouse clicks away. But you have to WANT TO do this. We are the most empowered people who ever lived on the plant, but it take time to sort out the facts and draw conclusions.
Hard to know who or what to believe anymore about anything current.
Thanks for your insights. Seem to be “right on” most of the time.